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What are the current guidelines for BRCA1 mutation carriers?
According to the current guidelines, individuals with BRCA1 mutations have the following recommendations:
- Annual MRI screening starting at age 25
- Addition of mammography starting at age 30
- Consider risk-reducing mastectomy
- Risk-reducing salpingo-oophorectomy recommended between ages 35-40
- No proven benefit from ovarian screening
Source: GeNotes ID: GN2023-05, "Management of BRCA1/2 mutation carriers", Last updated: November 2024